Hot Melt Extruders - HME A20 (Commercial Scale)

Hot Melt Extruders - HME A20 (Commercial Scale)
Hot Melt Extruders - HME A20 (Commercial Scale)
Hot Melt Extruders - HME A20 (Commercial Scale)
Hot Melt Extruders - HME A20 (Commercial Scale)
Hot Melt Extruders - HME A20 (Commercial Scale)
Hot Melt Extruders - HME A20 (Commercial Scale)
Hot Melt Extruders - HME A20 (Commercial Scale)
Hot Melt Extruders - HME A20 (Commercial Scale)

Hot Melt Extruders - HME A20 (Commercial Scale)

The Schenergix HME A20 is designed for high-capacity commercial-scale pharmaceutical and nutraceutical manufacturing. Hot Melt Extrusion is a continuous process that has become essential for improving drug solubility, bioavailability, and controlled release profiles. The A20 also supports both wet and dry granulation using HME, giving manufacturers the flexibility to develop a wider range of formulations.

Combining performance, flexibility, and reliability, the A20 is a trusted choice for large-scale production environments. With convertible barrel lengths and a throughput of up to 15 kg/h, it enables efficient, solvent-free processing. Its advanced screw design, coupled with precise heating and cooling controls, ensures consistent product quality and scalability. Built with safety and compliance in mind, the A20 can be supplied with flexible or rigid isolators, meeting the highest containment standards.

Key Features include:

  • Commercial-scale throughput up to 15 kg/h
  • Supports wet and dry granulation using HME
  • Convertible barrel length L/D 20:1 or 40:1
  • Co-rotating twin screw processor with modular screw design
  • Available with flexible or rigid isolator for OEL-5 compliance
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Design Features

  • Co-rotating twin screw processor
  • Modular screw design with convertible L/D 20:1 or 40:1
  • Skid-mounted chill-roll and pelletiser for extrudate cutting
  • Available with flexible or rigid isolator up to OEL-5
  • Technical Specification

  • Barrel bore diameter: 20 mm
  • Barrel length (convertible): L/D 20:1 or 40:1
  • Throughput (formulation dependent): up to 15.0 kg/h
  • Minimum batch size: 100 g
  • Maximum motor power: 7.5 kW
  • Maximum screw speed: 1100 rpm
  • Heating zones: 7
  • Cooling water: 20 L/min (8–18°C)
  • Electrical: 400V / 3ph+N / 40A
  • Dimensions (LxWxH): 2.3 x 0.7 x 1.9 m
  • Operational Benefit

  • Suitable for large-scale commercial production
  • Enhances solubility and bioavailability of APIs
  • Versatile feeding of solids, liquids, and gases
  • Easy to clean and compliant with 21 CFR-Part 11
  • Applications

  • API synthesis
  • Commercial scale
  • Solubility enhancement
  • Modified release
  • Taste masking
  • Fast dissolving films
  • Transdermal patches
  • Melt granulation
  • Wet granulation
  • Dry Granulation
  • Biomedical compounding
  • Supply Options

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