Hot Melt Extruders - HME A16 (Pilot or Commercial Scale)

Hot Melt Extruders - HME A16 (Pilot or Commercial Scale)
Hot Melt Extruders - HME A16 (Pilot or Commercial Scale)
Hot Melt Extruders - HME A16 (Pilot or Commercial Scale)
Hot Melt Extruders - HME A16 (Pilot or Commercial Scale)
Hot Melt Extruders - HME A16 (Pilot or Commercial Scale)
Hot Melt Extruders - HME A16 (Pilot or Commercial Scale)
Hot Melt Extruders - HME A16 (Pilot or Commercial Scale)
Hot Melt Extruders - HME A16 (Pilot or Commercial Scale)

Hot Melt Extruders - HME A16 (Pilot or Commercial Scale)

The Schenergix HME A16 bridges the gap between pilot-scale development and full commercial production. Hot Melt Extrusion has transformed modern drug manufacturing by offering a solvent-free process that enhances drug solubility, stability, and delivery. The A16 supports both wet and dry granulation processes using HME, providing manufacturers with greater flexibility in formulation development.

Designed for process optimisation and mid-scale manufacturing, the A16 helps companies scale smoothly from research to market-ready production. With a throughput of up to 5 kg/h, it offers reliable performance while maintaining scalability and precision. Its modular design, ease of operation, and compatibility with auxiliary equipment such as chill-roll and pelletising units make it an efficient and versatile tool for continuous manufacturing environments.

Key Features include:

  • Supports wet and dry granulation using HME
  • Pilot or commercial-scale throughput up to 5 kg/h
  • Barrel length L/D 40:1
  • Modular screw design with self-cleaning capability
  • Compatible with chill-roll and pelletiser units
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Design Features

  • Twin screw co-rotating processor
  • Modular screw design with L/D 40:1
  • Compatible with chill-roll and pelletiser units
  • Option for flexible or rigid isolator up to OEL-5
  • Technical Specification

  • Barrel bore diameter: 16 mm
  • Barrel length: L/D 40:1
  • Throughput (formulation dependent): up to 5.0 kg/h
  • Minimum batch size: 50 g
  • Maximum motor power: 3.7 kW
  • Maximum screw speed: 1100 rpm
  • Heating zones: 7
  • Cooling water: 12 L/min (8–18°C)
  • Electrical: 400V / 3ph+N / 40A
  • Dimensions (LxWxH): 2.0 x 0.6 x 1.25 m
  • Operational Benefit

  • Flexible for pilot or mid-scale production
  • Scalable pathway from R&D to commercial scale
  • Easy cleaning and maintenance
  • Full process control and compliance
  • Applications

  • API synthesis
  • Research and development
  • Solubility enhancement
  • Modified release
  • Taste masking
  • Fast dissolving films
  • Transdermal patches
  • Melt granulation
  • Wet granulation
  • Dry Granulation
  • Biomedical compounding
  • Supply Options

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